• Family-based association study of the loci 2 and 3 in a European restless legs syndrome population 

      Kemlink, D.; Polo, O.; Montagna, P.; Provini, F.; Stiasny-Kolster, K.; Oertel, W.; de Weerd, A.; Nevsimalova, S.; Sonka, K.; Hogl, B.; Frauscher, B.; Poewe, W.; Trenkwalder, C.; Pramstaller, P. P.; Ferini-Strambi, L.; Zucconi, M.; Konofal, E.; Arnulf, I.; Hadjigeorgiou, G. M.; Happe, S.; Klein, C.; Hiller, A.; Lichtner, P.; Meitinger, T.; Muller-Myshok, B.; Winkelmann, J. (2007)
      Three loci for the restless legs syndrome (RLS) on chromosomes 12q, 14q, and 9p (RLS 1, RLS2, and RLS3) have been mapped, but no gene has been identified as yet. RLS1 has been confirmed in families from three different ...
    • Progressive development of augmentation during long-term treatment with levodopa in restless legs syndrome: results of a prospective multi-center study 

      Hogl, B.; Garcia-Borreguero, D.; Kohnen, R.; Ferini-Strambi, L.; Hadjigeorgiou, G.; Hornyak, M.; de Weerd, A.; Happe, S.; Stiasny-Kolster, K.; Gschliesser, V.; Egatz, R.; Frauscher, B.; Benes, H.; Trenkwalder, C.; Hening, W. A.; Allen, R. P. (2010)
      The European Restless Legs Syndrome (RLS) Study Group performed the first multi-center, long-term study systematically evaluating RLS augmentation under levodopa treatment. This prospective, open-label 6-month study was ...
    • Suggestive evidence for linkage for restless legs syndrome on chromosome 19p13 

      Kemlink, D.; Plazzi, G.; Vetrugno, R.; Provini, F.; Polo, O.; Stiasny-Kolster, K.; Oertel, W.; Nevsimalova, S.; Sonka, K.; Högl, B.; Frauscher, B.; Hadjigeorgiou, G. M.; Pramstaller, P. P.; Lichtner, P.; Meitinger, T.; Müller-Myshok, B.; Winkelmann, J.; Montagna, P. (2008)
      Five loci for restless legs syndrome (RLS) on chromosomes 12q, 14q, 9p, 2q, and 20p (RLS1-RLS5) have been mapped in RLS families, with a recessive in the first and autosomal-dominant mode of inheritance in the latter cases. ...
    • Validation of the Augmentation Severity Rating Scale (ASRS): A multicentric, prospective study with levodopa on restless legs syndrome 

      García-Borreguero, D.; Kohnen, R.; Högl, B.; Ferini-Strambi, L.; Hadjigeorgiou, G. M.; Hornyak, M.; de Weerd, A. W.; Happe, S.; Stiasny-Kolster, K.; Gschliesser, V.; Egatz, R.; Cabrero, B.; Frauscher, B.; Trenkwalder, C.; Hening, W. A.; Allen, R. P. (2007)
      Background: Augmentation is the main complication during long-term dopaminergic treatment of restless legs syndrome (RLS) and reflects an overall increase in RLS severity. Its severity varies considerably from a minor ...